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The Osteomyelitis Center of Central Florida focuses on the treatment and preservation of bone infections only of the lower leg, ankle, and foot. This center is a private clinic founder by myself, Dr. Karr. Initially you will be seen and evaluated in my private clinic. Please contact the office at 863-646-5960 for an appointment and forward your clinical information to email@example.com or by mail prior to your first visit after reviewing the " Patients - In Preparation Of Your Office Visit/Consultation" tab to the left. Please understand we are not a referral service. If you have a bone infection of the lower leg, ankle, or foot you need to be seen in our clinic to help you.
Typically from that clinic evaluation, if appropriate, you will be scheduled for surgery to address your bone infection. I can not stress enough that to provide you a smooth evaluation and transition to possible resolution it is extremely important to review and follow the instructions at the left tab entitled " Patients - In Preparation Of Your Office Visit/Consultation".
A thorough evaluation providing a collective, advanced, and effective treatment plan for your bone infection. It is within this environment that the patient will experience a team approach to the treatment of their bone infection. You will be evaluated for other factors that negatively impact healing and will provide the support needed during the healing process to allow the patient to heal and return to family, hobbies, and work. Thus there may be other factors such as lower extremity circulation, tobacco use, diabetes, or compliance.
WHATS GOING ON
October 13, 2014 Mulheim, Germany
Dr. Karr will be attending an osteomyelitis cadaver meeting attended by surgeons from Germany, Italy, Spain, Denmark, UK, Switzerland, Austria, Netherlands and Poland.
September is PAD Awareness Month
June 26, 2014 at 6 pm Dinner on DFU's and growth factors hosted by The Osteomyelitis Center. please rsvp and attend at 1-813-732-2607
January 17, 2014
Advances in the Treatment of Osteomyelitis - SAM 2014 symposium in Orlando, FL. www.fpma.com
9-20-13 Just published by Dr. Karr and Dr. Pham:
Online Exclusive: A Case Presentation: The Successful Management of Complicated Wounds in the Presence of an Infected Knee Prosthesis With Silver Antimicrobial Negative Pressure Dressing and a Negative Pressure Wound Therapy Device. www.woundresearch.com.
Dr. Jeffrey C. Karr
The History of the Center, Research, and Outcomes - What It Means to you.
The following is summery of the work done for the Percutaneous Antibiotic Delivery Technique (PAD-T). This technique was the first such technique in treating ostemyelitis not only within the United States but globally. My experience with osteomyelitis will allow me to provide the highest level of care for your lower extremity bone infection. I am here to help you.
Dr. Jeffrey C Karr is the founder and director of The Osteomyelitis Center of Central Florida. The Percutaneous Antibiotic Delivery Technique (PAD-T) is the first such percutaneous delivery technique for treating ostemyelitis not only within the United States but globally.
The PAD-T was invented, developed, and successfully used by Dr. Jeffrey C. Karr in 2009 as a means to deliver antibiotics percutaneously with a flowable bone void filler carrier into an area of bone infection allowing complete bone penetration and contact with the adherent bone surface bacteria/biofilm obtaining significant drug elusion and drug levels in the area of bone infection. The PAD-T involves a small percutaneous skin incision followed by a small bone cortex incision into the infected bone. This technique avoids a more invasive, some times multiple bone surgeries, such as placing and removing non-absorbable antibiotic beads. The PAD-T minimizes time away from work, does not require external fixation, and generally requires no change in weight bearing status. Irrigation and spongiosum bone cultures can be done through the bone cortex incision.
First bone void filler for osteomyelitis white paper - Karr, JC. Management of a Diabetic Patient Presenting with Forefoot Osteomyelitis Utilizing Cerament™|Bone Void Filler Impregnated with Vancomycin– Off Label Use. White paper. Bone Support. June 2009.
First bone void filler for osteomyelitis publication - Karr, JC. Management of a Diabetic Patient Presenting with Forefoot Osteomyelitis: The use of Cerament™ |Bone Void Filler Impregnated with Vancomycin – An off Label Use. The Journal of Diabetic Foot Complications: 2009, 1 (4), No. 3. pp. 94-100.
Symposium presentation - Biocompatible, Injectable Ceramic Antibiotic Impregnated Bone Substitute (Cerament) Minimal Inhibitory Concentration Against Methacillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa. APMA Nation meeting. Toronto, Canada. July 2009.
Product development for Bone Support using Cerament bone void filler as a flowable carrie vehicle with antibiotics to treat osteomyelitis 2009 - 2011.
Bacterial in vitro publication - Karr, JC, Keriazes G, Lautetta J. In Vitro Antimicrobial Activity of Calcium Sulfate and Hydroxyapatite (Cerament™| Bone Void Filler) Discs Utilizing Heat Sensitive and Heat Non-Sensitive Antibiotics against Methicillin Resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Journal of American Podiatric Medical Association Journal. Vol 101, No. 2, March/April 2011.
Symposium presentation - IN VITRO ANTIMICROBIAL ACTIVITY OF CALCIUM SULFATE AND HYDROXYAPATITE DISC OF HEAT SENSITIVE AND HEAT NON-SENSITIVE ANTIBIOTICS AGAINST METHICILLIN RESISTANT STAPHLOCOCCUS AUREUS (MRSA) AND PSEUDOMONAS AERUGINOSA. European Bone and Joint Infectious Disease Society. September 14-17, 2011 Copenhagen, Denmark.
Numerous white papers for Bone Support - #1 Fibular Osteomyelitis Following Ankle Surgery, Management with Flowable Percutaneous Calcium Sulfate and Hydroxyapitite (Cerament Bone Void Filler) and Vancomyacin, #2 Calcaneal Osteomyelitis Following Elective Foot Surgery and Management with Flowable Percutaneous Calcium Sulfate and Hydroxyapitite (Cerament Bone Void Filler) with Tobramycin and Vancomyacin. #3 The Management of Infected Ankle Arthrodesis with Removal of Internal Fixation and Intra-osseous Delivery of Calcium Sulfate and Hydroxyapitite (Cerament Bone Void Filler) with Vancomyacin #4 Mid-foot Charcot deformity with Osteomyelitis and Diabetic Foot Ulcers: Management with Flowable Percutaneous Calcium Sulfate and Hydroxyapitite (Cerament Bone Void Filler) with Vancomyacin 2011.
Physician education - BGU Krankenhaus Hospital Duisberg, Germany September 13, 2011.
Cerament – Clinical Results in Osteomyelitis
Physician education - University Hospital Mainz, Germany September 14, 2011. Bone Void Filler Cerament for Restorative Trauma and Osteomyelitis
Symposium presentation - European Bone and Joint Infectious Disease Society. September 14-17, 2011 Copenhagen,Denmark. PATIENT CASE SERIES OF INTRAOSSEOUS OSTEOMYEILTIS TRETAEMENT WITH CALCIUM SULFATE AND HYDROXYAPITITE BONE VOID FILLER IMPREGNATED WITH EITHER ANTIBIOTIC OR ANTIFUNGAL MEDICATION. 2011.
The Osteomyelitis Center of Central Florida Clinic and website launched 2012.
USA Patent (US 20120129761 A1) May 24, 2012. Preparation of bone cement compositions
Symposium presentation - European Bone and Joint Infectious Disease Society. Percutaneous antibiotic delivery techinique for osteomyelitis. September 20-22, 2012 Montreux, Switzerland
Symposium presentation - TM’s 1st World Virology and Microbiology Online conference. Session 8: Anti-Infection Treatments 14:30 PM – 16:00 PM Session Chair: Dr. David H. Van Thiel. Presentation Title: In vitro anti-bacterial and anti-fungal properties and human osteomyelitis management outcomes with calcium sulfate and hydroxyapatite (cerement) bone void filler impregnated with either antibiotic or antifungal medication. 2012.
Symposium presentation - TM’s 2nd World Virology and Microbiology Online conference. Session 8: Anti-Infection Treatments 14:30 PM – 16:00 PM Session Chair: Dr. David H. Van Thiel. Presentation Title: Treatment of Osteomyelitis with a percutaneous approach. 2013.
Physician teaching - Cadaver workshop for osteomyelitis. Dusseldorf, Germany. Bone Support.
Physical education - Advances in the Treatment of Osteomyelitis - SAM 2014 symposium in Orlando, FL. www.fpma.com
Fungal in vitro publication - Karr, JC, Lautetta J. In Vitro Anti-fungal Disc Activity of Calcium Sulfate and Hydroxyapatite (Cerament™| Bone Void Filler) Loaded with Amphotericin B or Voriconazole for Consideration in Adjunctive Osteomyelitis Management. JAPMA Feb 105(2) 2015
Point-Counterpoint: Is Surgical Treatment The Best Option For Forefoot Osteomyelitis? Podiatry Today
July 3, 2016.
Physician education - February 2nd 2016, Online discussion about osteomyelitis treatment at Podiatricsuccess.com. This is an open forum where you can participate and ask questions.
Technique/procedure publication - An Overview of the Percutaneous Antibiotic Delivery Technique for Osteomyelitis Treatment and aCase Study of Calcaneal Osteomyelitis. Journal of the American Podiatric Medical Association,Vol. 107, No. 6, November 2017: 511-515.
Pending for publication May/June 2018 - Karr, JC. Lower Extremity Osteomyelitis Treatment Utilizing Calcium Sulfate/Hydroxyapatite Bone Void Filler With Antibiotics: Seven-Year Retrospective Study.
- Contact Information
- A message from Dr. Karr with an overview of the Center and Osteomyelitis
- Patients - In preparation of your office visit/consultation
- Patients - In preparation of your on line questions
- Percutaneous Antibiotic Delivery Technique (PAD-T) Video - click on this tab too see the videos, Science, Instrumentation Layout, Technique Description, and Approaches
- Patient outcomes
- Osteomyelitis treatment options
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